Hot-melt sub- and outercoating combined with enteric aqueous coating to improve the stability of aspirin tablets
Aspirin is apt to hydrolyze.In order to improve its stability, a new method has been developed involving the application of hot-melt sub- and outercoating combined with enteric aqueous coating.The main aim was to investigate the influence of these factors on the stability of ASA and understand how they work.Satisfactory storage stability were obtai